I123Iodine 123

Iodine -123 is a radioisotope used in single photon computed tomography (SPECT). It has a half-life of 13.2h It is mainly used and has been approved to confirm the diagnosis of Parkinson Disease by helping visualising the dopamine transporter levels in the brain and also for thyroid imaging.

To produce Iodine 123,
we recommend this production route:

  • Recommended

    Cyclone:

    Cyclone® IKON

    Download the brochure

    123I can be produced on a cyclotron using proton bombardment (28- 30MeV) of a 124Xenon gas target.

    More about Cyclone® IKON

    Target:

    123 gas target

    Gas target loaded with enriched 124Xenon to provide 123I by natural decay. The gas target has a cryogenic recovery system for 124Xe (working in closed loop). The 123I is extracted by washing target with pure water.

    Chemistry:

    Pinctada®

    The target wash solution is purified by two ion exchange columns to provide a concentrated NaI solution for dispensing or labelling

    More about Radioalogen Chemistry

  • Recommended

    Cyclone:

    Cyclone® 30 XP

    Download the brochure

    123I can be produced on a cyclotron using proton bombardment (28- 30MeV) of a 124Xenon gas target.

    More about Cyclone® 30 XP

    Target:

    Nirta® XETI gas target

    Gas target loaded with enriched 124Xenon to provide 123I by natural decay. The gas target has a cryogenic recovery system for 124Xe (working in closed loop). The 123I is extracted by washing target with pure water.

    Chemistry:

    Pinctada® 123I

    The target wash solution is purified by two ion exchange columns to provide a concentrated NaI solution for dispensing or labelling

    More about Radioalogen Chemistry

  • Alternative

    Cyclone:

    Cyclone® KIUBE

    Download the brochure

    123I can also be produced using a solid target and an energy of 14 MeV

    More about Cyclone® KIUBE

    Target:

    Nirta® solid target

    Nirta® Solid target can be used for the irradiation of enriched 123Te via  123Te(p,n)123I nuclear reaction.

    More about Nirta® solid target

    Chemistry:

    HighMOR®

    The radioiodine separation is accomplished via thermo-distillation with the HighMOR® system at  high temperature to release the iodine. Iodine is then trapped into a solution. This fully automated process is controlled by user-friendly software interface allowing separation in less than 4h.

    More about HighMOR®

  • Alternative

    Cyclone:

    Cyclone® 30 XP

    Download the brochure

    123I can also be produced using a solid target and variable energy.

    More about Cyclone® 30 XP

    Target:

    Nirta® solid target

    Nirta® Solid target can be used for the irradiation of enriched 123Te via  123Te(p,n)123I nuclear reaction.

    More about Nirta® solid target

    Chemistry:

    Thermo distillation

    The radioiodine separation is accomplished via thermo distillation at high temperature to release the iodine. Iodine is then trapped into a solution. This fully automated process is controlled by user-friendly software interface allowing separation in less than 4h.

Scientific publications