Zr89Zirconium 89

Zirconium-89 is a radioisotope used in positron emission tomography (PET). It has a long half-life of 78.4 hours, which allows centralized distribution. Due to its appropriate half-life, this isotope has opened possibilities for PET imaging in the visualisation of in-vivo processes with slow pharmacokinetics such as radiolabelled monoclonal antibodies.

To produce Zirconium 89,
we recommend this production route:

  • Recommended

    Cyclone:

    Cyclone® KIUBE

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    89Zr is produced on a cyclotron using proton bombardment (14-14,5MeV). This can be obtained using the Cyclone® KIUBE Custom Energy feature or a degrader foil.

    More about Cyclone® KIUBE

    Target:

    Nirta® solid target

    The production of 89Zr, from the 89Y( p,n)89Zr only requires a natural 89Y-foil as target material. This foil is then placed onto a aluminium/copper disk in the Nirta® Solid target. The target material is then irradiated and it is manually or automatically transferred to a hot cell.

    More about Nirta® solid target

    Chemistry:

    Pinctada® Metal

    The irradiated target material is then dissolved and post-processed. Pinctada® platform is a complete industrial platform for the dissolution & purification of 89Zr-oxalate. After purification, the purified radioisotope is obtained in the form of 89Zr-oxalate and it can be used for further labelling manually or on Synthera®

    More about Pinctada® Metal

  • Alternative

    Cyclone:

    Cyclone® 30 XP

    Download the brochure

    89Zr can also be produced on the Cyclone® 30 XP using its variable energy.

    More about Cyclone® 30 XP

    Target:

    Nirta® solid target

    The production of 89Zr, from the 89Y( p,n)89Zr only requires a natural 89Y-foil as target material. This foil is then placed onto a aluminium/copper disk in the Nirta® Solid target. The target material is then irradiated and it is manually or automatically transferred to a hot cell.

    More about Nirta® solid target

    Chemistry:

    Pinctada® Metal

    The irradiated target material is then dissolved and post-processed. Pinctada® platform is a complete industrial platform for the dissolution & purification of 89Zr-oxalate. After purification, the purified radioisotope is obtained in the form of 89Zr-oxalate and it can be used for further labelling manually or on Synthera®

    More about Pinctada® Metal

  • Alternative

    Cyclone:

    Cyclone® IKON

    Download the brochure

    89Zr can also be produced on the Cyclone® IKON using its variable energy.

    More about Cyclone® IKON

    Target:

    Nirta® solid target

    The production of 89Zr, from the 89Y( p,n)89Zr only requires a natural 89Y-foil as target material. This foil is then placed onto a aluminium/copper disk in the Nirta® Solid target. The target material is then irradiated and it is manually or automatically transferred to a hot cell.

    More about Nirta® solid target

    Chemistry:

    Pinctada® Metal

    The irradiated target material is then dissolved and post-processed. Pinctada® platform is a complete industrial platform for the dissolution & purification of 89Zr-oxalate. After purification, the purified radioisotope is obtained in the form of 89Zr-oxalate and it can be used for further labelling manually or on Synthera®

    More about Pinctada® Metal

Scientific publications